2-(4-Fluorophenyl)pyridine

Name: 2-(4-Fluorophenyl)pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 58861-53-3
Cat. No. CS-0060614
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 58861-53-3

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Description

2-(4-Fluorophenyl)pyridine is a fluorinated heteroaryl building block featuring a pyridine core linked to a para-fluorinated phenyl group. This electron-deficient scaffold enhances π-conjugation and facilitates metal-catalyzed coupling reactions. The molecule exhibits enhanced stability and solubility in organic media, enabling efficient integration into advanced materials and pharmaceutical intermediates.

Application

2-(4-Fluorophenyl)pyridine serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of biologically active heterocycles and functional organic semiconductors. Its fluorinated aryl group enhances metabolic stability and modulates electronic properties, while the pyridine core provides a robust site for transition metal-catalyzed coupling reactions. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating efficient incorporation into complex molecular architectures.

General Information

CAS No. 58861-53-3
Cat. No. CS-0060614
Purity ≥98%
MDL No. None
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₈FN
Molecular Weight 173.19
Synonym(s) 1-(2-Pyridinyl)-4-fluorobenzene
SMILES C1=CC=NC(=C1)C2=CC=C(C=C2)F

Computational Chemistry Data

TPSA 12.89
LogP 2.8877
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Material Science Material Building Blocks Ligands for Functional Metal Complexes Phenylpyridine Ligands

Key Words

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2-(4-Fluorophenyl)pyridine

CAS No. 58861-53-3

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