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CS-W001157 4
Total: USD 88.00

3-(Boc-amino)propyl bromide

  • CAS No. 83948-53-2

  • Cat. No. CS-M1109
  • Purity≥95%
  • MDL No.MFCD02683429

*For research and further manufacturing use only, not for direct human use.

3-(Boc-amino)propyl bromide|CS-M1109

Structure of 83948-53-2

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General Information

  • CAS No. 83948-53-2
  • Cat. No. CS-M1109
  • Purity ≥95%
  • MDL No. MFCD02683429
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆BrNO₂
  • Molecular Weight 238.12
  • Synonym(s) None
  • SMILES O=C(NCCCBr)OC(C)(C)C

Description

3-(Boc-amino)propyl bromide features a stable Boc-protected amine tethered to a reactive alkyl bromide handle, enabling efficient conjugation in peptide synthesis and polymer functionalization. This bench-stable reagent facilitates site-specific derivatization under mild conditions, offering reliable coupling efficiency and compatibility with diverse reaction environments.

Synthesis

  • Route1

    References

    • Huang, Adela Ya-Ting; Tsai, Ching-Hua; Chen, Hsing-Yin; Chen, Hui-Ting; Lu, Chi-Yu; Lin, Yu-Ting; Kao, Chai-Lin Chemical Communications, 2013 , vol. 49, # 51 p. 5784 - 5786
  • Route2

    References

    • Machida, Shinnosuke; Usuba, Kakeru; Blaskovich, Michelle A.; Yano, Akiko; Harada, Kazuo; Sebti, Said M.; Kato, Nobuo; Ohkanda, Junko Chemistry - A European Journal, 2008 , vol. 14, # 5 p. 1392 - 1401
  • Route3
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      3-(Boc-amino)propyl bromide|CS-M1109
      83948-53-2

    References

    • Levy, Daniel E.; Wang, Dan-Xiong; Lu, Qing; Chen, Zheng; Perumattam, John; Xu, Yong-jin; Liclican, Albert; Higaki, Jeffrey; Dong, Hanmin; Laney, Maureen; Mavunkel, Babu; Dugar, Sundeep Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 7 p. 2390 - 2394

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   2.2961
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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