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tert-Butyl (3-bromopropyl)(methyl)carbamate

  • CAS No. 828272-19-1

  • Cat. No. CS-0139180
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (3-bromopropyl)(methyl)carbamate|CS-0139180

Structure of 828272-19-1

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General Information

  • CAS No. 828272-19-1
  • Cat. No. CS-0139180
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈BrNO₂
  • Molecular Weight 252.15
  • Synonym(s) 3-Bromo-N-methyl-N-boc-propylamine
  • SMILES O=C(OC(C)(C)C)N(CCCBr)C

Description

tert-Butyl (3-bromopropyl)(methyl)carbamate features a bromoalkyl handle flanked by a methyl-substituted carbamate and sterically shielded tert-butyl group, enabling selective conjugation under mild conditions. This bench-stable reagent integrates readily into bioconjugation workflows, delivering controlled functionalization of nucleophiles without catalyst dependency.

Application

tert-Butyl (3-bromopropyl)(methyl)carbamate serves as a versatile bifunctional building block, enabling efficient introduction of both a bromoalkyl chain and a protected amine moiety in synthetic sequences. The tert-butyl carbamate group provides excellent stability under basic conditions and facilitates straightforward deprotection via mild acidolysis. Its reactivity profile supports reliable alkylation reactions and incorporation into heterocyclic scaffolds, making it a practical choice for medicinal chemistry and process-scale synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   2.6383
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

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