(9H-Fluoren-9-yl)methyl (3-bromopropyl)carbamate

Name: (9H-Fluoren-9-yl)methyl (3-bromopropyl)carbamate
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CAS No. 186663-83-2
Cat. No. CS-0059690
Purity≥96%
MDL No.MFCD06411708

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(9H-Fluoren-9-yl)methyl (3-bromopropyl)carbamate|CS-0059690

Structure of 186663-83-2

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General Information

CAS No. 186663-83-2
Cat. No. CS-0059690
Purity ≥96%
MDL No. MFCD06411708
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₁₈BrNO₂
Molecular Weight 360.25
Synonym(s) methyl (3-bromopropyl)
SMILES BrCCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O

Description

This fluorenylmethyl carbamate derivative features a reactive bromopropyl handle for facile conjugation. The 9-fluorenylmethyl group provides excellent solubility and stability during solid-phase synthesis, while the pendant bromide enables efficient coupling reactions in peptide and oligonucleotide chemistry workflows.

Application

(9H-Fluoren-9-yl)methyl (3-bromopropyl)carbamate serves as a versatile bifunctional building block in peptide and oligonucleotide synthesis, enabling efficient conjugation via its bromoalkyl handle. The fluorenylmethoxycarbonyl (Fmoc) group provides orthogonal protection for amines, while the pendant 3-bromopropyl moiety facilitates nucleophilic substitution with thiols, amines, or azide derivatives. Its bench-stable nature and compatibility with standard purification methods make it ideal for modular assembly of bioconjugates and functionalized scaffolds.

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

TPSA 38.33
LogP 4.3101
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 5

Other Classifications

Building Blocks Functional Group Fmoc

Building Blocks Functional Group Amine

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(9H-Fluoren-9-yl)methyl (3-bromopropyl)carbamate

CAS No. 186663-83-2

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