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CS-W001157 4
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2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline

  • CAS No. 761440-75-9

  • Cat. No. CS-M0379
  • Purity≥98%
  • MDL No.MFCD12827955

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline|CS-M0379

Structure of 761440-75-9

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General Information

  • CAS No. 761440-75-9
  • Cat. No. CS-M0379
  • Purity ≥98%
  • MDL No. MFCD12827955
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₄O
  • Molecular Weight 304.43
  • Synonym(s) 2-Methoxy-4-[4-(4-Methylpiperazin-1-yl)piperidin-1-yl]aniline
  • SMILES NC1=C(OC)C=C(C=C1)N2CCC(CC2)N3CCN(C)CC3

Description

This aniline derivative features a methoxy group at the 2-position and a complex piperazine-piperidine side chain at the 4-position, delivering enhanced solubility and metabolic stability. The electron-donating methoxy moiety modulates electronic properties, while the tertiary amine system enables efficient conjugation in medicinal chemistry applications.

Application

2-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline serves as a versatile building block for medicinal chemistry campaigns, enabling efficient access to complex heterocyclic scaffolds. Its amine functionality facilitates conjugation in Suzuki and Buchwald–Hartwig reactions, while the methoxy group provides orthogonal reactivity. The molecule exhibits good bench stability and solubility, supporting straightforward purification and integration into multi-step synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.97
  • LogP   1.4936
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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