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CS-W001157 4
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3-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline

  • CAS No. 1254058-34-8

  • Cat. No. CS-0015773
  • Purity≥98%
  • MDL No.MFCD28129029

*For research and further manufacturing use only, not for direct human use.

3-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline|CS-0015773

Structure of 1254058-34-8

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General Information

  • CAS No. 1254058-34-8
  • Cat. No. CS-0015773
  • Purity ≥98%
  • MDL No. MFCD28129029
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₈N₄O
  • Molecular Weight 304.43
  • Synonym(s) 3-Methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)aniline
  • SMILES COC1=C(N2CCC(N3CCN(C)CC3)CC2)C=CC(N)=C1

Description

This aniline derivative features a methoxy-substituted aromatic ring linked to a piperazine-piperidine hybrid side chain, delivering enhanced solubility and metabolic stability. The electron-donating methoxy group modulates electronic properties, while the tertiary amine moieties enable efficient conjugation in bioconjugation workflows. Designed for use in medicinal chemistry scaffolds and targeted drug delivery systems.

Application

3-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]aniline serves as a versatile building block in medicinal chemistry, enabling the construction of complex heterocyclic scaffolds. Its amine functionality facilitates standard coupling reactions, while the methoxy and piperazine-piperidine moieties provide favorable solubility and metabolic stability. The molecule exhibits bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.97
  • LogP   1.4936
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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