Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

AP24592

  • CAS No. 694499-26-8

  • Cat. No. CS-M1483
  • Purity≥97%
  • MDL No.MFCD09909924

*For research and further manufacturing use only, not for direct human use.

AP24592|CS-M1483

Structure of 694499-26-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 694499-26-8
  • Cat. No. CS-M1483
  • Purity ≥97%
  • MDL No. MFCD09909924
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈F₃N₃
  • Molecular Weight 273.30
  • Synonym(s) None
  • SMILES NC(C=C1C(F)(F)F)=CC=C1CN2CCN(C)CC2

Description

AP24592 is a bench-stable, moisture-tolerant boronate ester featuring a para-nitrophenyl group that enables efficient coupling in palladium-catalyzed cross-coupling reactions. This robust reagent integrates seamlessly into synthetic workflows requiring high functional group compatibility and reliable performance under standard conditions.

Application

AP24592 serves as a versatile building block for constructing nitrogen-containing heterocycles, particularly in the synthesis of pyrrolidines and piperidines. Its well-defined reactivity enables efficient cyclization under mild conditions, offering high functional group tolerance and excellent bench stability. The compound facilitates straightforward purification and is compatible with standard coupling protocols, making it ideal for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Organic Process Research and Development, , vol. 12, # 6 p. 1146 - 1155
  • Route2
    • [4-Amino-2-(trifluoromethyl)phenyl](4-methyl-1-piperazinyl)methanone|CS-0151088
      853297-04-8
    • ~97%
    • In-stock
      AP24592|CS-M1483
      694499-26-8

    References

    • Bioorganic and Medicinal Chemistry, , vol. 18, # 20 p. 7150 - 7163
  • Route3
    • null|null
      709045-30-7
    • ~%
    • In-stock
      AP24592|CS-M1483
      694499-26-8

    References

    • WO2004/52884 A1, ; Page 54 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   32.5
  • LogP   2.035
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • AP24592 sigmaAP24592 manufacturerAP24592 priceAP24592 structureAP24592 SDSbuy AP24592AP24592 supplierAP24592 usesAP24592 molecular weightprice of AP24592AP24592 chemical name formula of AP24592
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label