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CS-W001157 4
Total: USD 88.00

3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine Hydrochloride

  • CAS No. 741736-95-8

  • Cat. No. CS-0005905
  • Molecule weight238.64
  • Purity≥98%
  • MDL No.MFCD13151972

*For research and further manufacturing use only, not for direct human use.

3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine Hydrochloride|CS-0005905

Structure of 741736-95-8

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General Information

  • CAS No. 741736-95-8
  • Cat. No. CS-0005905
  • Purity ≥98%
  • MDL No. MFCD13151972
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀ClF₃N₂
  • Molecular Weight 238.64
  • Synonym(s) 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
  • SMILES FC(F)(F)C1=CC2=C(N=C1)CCNC2.Cl

Synthesis

  • Route1
    • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine|CS-0477154
      624734-27-6
    • ~72%
    • 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine Hydrochloride|CS-0005905
      741736-95-8

    References

    • MERCK and CO., INC. Patent: WO2005/44264 A1, 2005 ; Location in patent: Page/Page column 11; 22-23 ; WO 2005/044264 A1
  • Route2
    • tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate|CS-0005904
      624734-26-5
    • ~80%
    • 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine Hydrochloride|CS-0005905
      741736-95-8

    References

    • ARES TRADING S.A.; JORAND-LEBRUN, Catherine; SWINNEN, Dominique; GERBER, Patrick; KULKARNI, Santosh Patent: WO2012/130915 A1, 2012 ; Location in patent: Page/Page column 63 ; WO 2012/130915 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   2.1679
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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