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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine

  • CAS No. 624734-27-6

  • Cat. No. CS-0477154
  • Molecule weight202.18
  • Purity≥98%
  • MDL No.MFCD10696336

*For research and further manufacturing use only, not for direct human use.

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine|CS-0477154

Structure of 624734-27-6

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General Information

  • CAS No. 624734-27-6
  • Cat. No. CS-0477154
  • Purity ≥98%
  • MDL No. MFCD10696336
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉F₃N₂
  • Molecular Weight 202.18
  • Synonym(s) intermediate 2
  • SMILES FC(F)(F)C1=CN=C2CCNCC2=C1

Synthesis

  • Route1
    • tert-Butyl 3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate|CS-0005904
      624734-26-5
    • ~10%
    • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine|CS-0477154
      624734-27-6

    References

    • MERCK and CO., INC. Patent: WO2005/105092 A2, 2005 ; Location in patent: Page/Page column 35 ; WO 2005/105092 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   1.7461
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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