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Structure of 723294-74-4
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3-Fluoro-5-iodobenzoic acid features a fluorinated benzene ring bearing iodine and carboxylic acid groups at meta positions, enabling selective cross-coupling reactions. The electron-withdrawing fluorine enhances reactivity in palladium-catalyzed transformations, while the iodide serves as a high-efficiency coupling handle. This compound offers excellent stability under standard bench conditions and integrates readily into complex molecular architectures.
3-Fluoro-5-iodobenzoic acid serves as a versatile building block for palladium-catalyzed cross-coupling reactions, enabling efficient access to substituted biaryls and heterocycles. The ortho-fluoro and meta-iodo groups provide orthogonal reactivity, facilitating sequential functionalization. Its bench-stable carboxylic acid functionality supports direct derivatization or use in amide coupling protocols, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: