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Structure of 1261837-87-9
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(3-Fluoro-5-iodophenyl)methanol features a fluorinated aromatic ring paired with a reactive benzyl alcohol group, enabling direct functionalization in cross-coupling and derivatization workflows. The electron-withdrawing fluorine substituent enhances regioselectivity, while the iodine moiety supports palladium-catalyzed transformations. This bench-stable reagent integrates efficiently into complex molecule synthesis.
(3-Fluoro-5-iodophenyl)methanol serves as a versatile building block in cross-coupling chemistry, enabling efficient Suzuki and Negishi reactions due to its stable aryl iodide functionality. The pendant alcohol group provides a handle for derivatization or protection, while the meta-fluoro substituent offers orthogonal reactivity in sequential transformations. Its bench-stable nature and compatibility with standard catalytic protocols make it well-suited for the synthesis of complex pharmaceutical intermediates and functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: