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CS-W001157 4
Total: USD 88.00

Mesitaldehyde

  • CAS No. 487-68-3

  • Cat. No. CS-W018185
  • Purity≥95%
  • MDL No.MFCD00003341

*For research and further manufacturing use only, not for direct human use.

Mesitaldehyde|CS-W018185

Structure of 487-68-3

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General Information

  • CAS No. 487-68-3
  • Cat. No. CS-W018185
  • Purity ≥95%
  • MDL No. MFCD00003341
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O
  • Molecular Weight None
  • Synonym(s) 2,4,6-Trimethylbenzaldehyde
  • SMILES O=CC1=C(C)C=C(C)C=C1C

Description

Mesitaldehyde features a sterically hindered trimethyl-substituted aromatic ring that imparts exceptional stability and resistance to oxidation. This electron-rich aldehyde integrates readily into condensation reactions, enabling efficient access to complex heterocyclic scaffolds under mild conditions.

Application

Mesitaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic systems and heterocycles. Its three methyl groups confer enhanced stability and facilitate electrophilic substitution reactions, while the aldehyde functionality allows for straightforward transformations including imine formation, aldol condensations, and reductive amination. The compound's bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • 2,4,6-Trimethylbenzaldehyde oxime|CS-1720267
      40188-34-9
    • ~93%
    • In-stock
      Mesitaldehyde|CS-W018185
      487-68-3

    References

    • Lou, Ji-Dong; Lu, Xiu Lian; Huang, Li-Hong; Zhang, Changhe; Wang, Qiang; Zou, Xiao-Nan Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2011 , vol. 41, # 10 p. 1278 - 1281
  • Route2

    References

    • Hullio, Ahmed Ali; Mastoi; Khan, Khalid Asian Journal of Chemistry, 2011 , vol. 23, # 12 p. 5411 - 5418
  • Route3

    References

    • Iinuma, Masataka; Moriyama, Katsuhiko; Togo, Hideo European Journal of Organic Chemistry, 2014 , vol. 2014, # 4 p. 772 - 780

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H315-H351-H411
Precautionary Statements : P264-P273-P280-P302+P352-P362-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.42436
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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