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Structure of 723294-75-5
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3-Fluoro-5-iodobenzonitrile is a fluorinated aryl iodide featuring a nitrile group at the para position, enabling efficient cross-coupling reactions. The electron-withdrawing nitrile and fluorine substituents enhance reactivity in palladium-catalyzed transformations. This bench-stable compound serves as a key building block for functionalized aromatic systems in medicinal chemistry and materials science.
3-Fluoro-5-iodobenzonitrile serves as a versatile building block in cross-coupling chemistry, enabling efficient Suzuki, Stille, and Negishi reactions due to its orthogonal reactivity profile. The nitrile group provides synthetic handle for downstream functionalization, while the fluorine substituent enhances metabolic stability in pharmaceutical intermediates. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step synthesis of bioactive heterocycles and advanced API scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: