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CS-W001157 4
Total: USD 88.00

2,6-Difluorobenzylamine

  • CAS No. 69385-30-4

  • Cat. No. CS-W018259
  • Purity≥96%
  • MDL No.MFCD00010144

*For research and further manufacturing use only, not for direct human use.

2,6-Difluorobenzylamine|CS-W018259

Structure of 69385-30-4

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General Information

  • CAS No. 69385-30-4
  • Cat. No. CS-W018259
  • Purity ≥96%
  • MDL No. MFCD00010144
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇F₂N
  • Molecular Weight 143.14
  • Synonym(s) 1-(2,6-Difluorophenyl)methanamine
  • SMILES NCC1=C(F)C=CC=C1F

Description

2,6-Difluorobenzylamine has been used in the synthesis of:(Z)-N1-(2,6-difluorobenzyl)-N2-(2-amino-1,2-dicyanovinyl)formamidine2,6-difluorobenzyl-guanidine hydrochloride

Application

2,6-Difluorobenzylamine serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via amine coupling and electrophilic substitution reactions. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the primary amine facilitates straightforward derivatization. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H314-H318
Precautionary Statements : P210-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.4235
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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