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CS-W001157 4
Total: USD 88.00

Bis-PEG1-NHS ester

  • CAS No. 65869-64-9

  • Cat. No. CS-0104991
  • Purity≥95%
  • MDL No.MFCD20226397

*For research and further manufacturing use only, not for direct human use.

Bis-PEG1-NHS ester|CS-0104991

Structure of 65869-64-9

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General Information

  • CAS No. 65869-64-9
  • Cat. No. CS-0104991
  • Purity ≥95%
  • MDL No. MFCD20226397
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₆N₂O₉
  • Molecular Weight 356.28
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCC(ON2C(CCC2=O)=O)=O

Description

Bis-PEG1-NHS ester features two reactive NHS groups separated by a short PEG spacer, enabling efficient conjugation to primary amines under physiological conditions. This bifunctional linker facilitates site-specific protein labeling and the construction of well-defined polymer-protein hybrids with enhanced solubility and stability.

Application

Bis-PEG1-NHS ester serves as a bifunctional crosslinking agent, enabling efficient conjugation of primary amines in peptides, proteins, and biomolecules. Its PEG1 spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester groups offer high reactivity under physiological conditions. Ideal for bioconjugation workflows requiring site-specific labeling and facile purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   136.59
  • LogP   -1.0024
  • H_Acceptors   9
  • H_Donors   0
  • Rotatable_Bonds   8

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