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CS-W001157 4
Total: USD 88.00

Bis-​PEG4-​NHS ester

  • CAS No. 1314378-11-4

  • Cat. No. CS-0104985
  • Purity≥97%
  • MDL No.MFCD20228963

*For research and further manufacturing use only, not for direct human use.

Bis-​PEG4-​NHS ester|CS-0104985

Structure of 1314378-11-4

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General Information

  • CAS No. 1314378-11-4
  • Cat. No. CS-0104985
  • Purity ≥97%
  • MDL No. MFCD20228963
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₈N₂O₁₂
  • Molecular Weight 488.44
  • Synonym(s) Bis-PEG4-NHS ester
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Description

Bis-PEG4-NHS ester enables efficient, site-specific conjugation in aqueous environments. This bifunctional reagent features two NHS ester groups flanking a PEG4 spacer, offering enhanced solubility and controlled spacing for biomolecule labeling or surface immobilization.

Application

Bis-PEG4-NHS ester serves as a bifunctional crosslinking agent enabling efficient conjugation of biomolecules and surface immobilization. The PEG4 spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester groups react readily with primary amines under physiological conditions. This reagent facilitates site-specific labeling and functionalization in protein bioconjugation, peptide modification, and solid-phase synthesis with minimal aggregation and excellent handling stability.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   164.28
  • LogP   -0.9526
  • H_Acceptors   12
  • H_Donors   0
  • Rotatable_Bonds   17

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