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CS-W001157 4
Total: USD 88.00

4-(2-Trifluoromethyl-pyridin-4-yloxy)-phenylamine

  • CAS No. 630125-71-2

  • Cat. No. CS-0340693
  • Molecule weight254.21
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(2-Trifluoromethyl-pyridin-4-yloxy)-phenylamine|CS-0340693

Structure of 630125-71-2

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General Information

  • CAS No. 630125-71-2
  • Cat. No. CS-0340693
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉F₃N₂O
  • Molecular Weight 254.21
  • Synonym(s) None
  • SMILES C1=C(C=CC(=C1)OC2=CC(=NC=C2)C(F)(F)F)N

Synthesis

  • Route1
    • 4-Fluoro-2-(trifluoromethyl)pyridine|CS-0235107
      850246-04-7
    • ~79%
    • 4-(2-Trifluoromethyl-pyridin-4-yloxy)-phenylamine|CS-0340693
      630125-71-2

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2005/35507 A2, 2005 ; Location in patent: Page/Page column 65 ; WO 2005/035507 A2
  • Route2
    • 4-Fluoro-2-(trifluoromethyl)pyridine|CS-0235107
      850246-04-7
    • null|null
      123-30-8
    • ~80%
    • 4-(2-Trifluoromethyl-pyridin-4-yloxy)-phenylamine|CS-0340693
      630125-71-2

    References

    • BAYER PHARMACEUTICALS CORPORATION Patent: WO2006/99231 A1, 2006 ; Location in patent: Page/Page column 50 ;
  • Route3
    • null|null
      630125-72-3
    • ~%
    • 4-(2-Trifluoromethyl-pyridin-4-yloxy)-phenylamine|CS-0340693
      630125-71-2

    References

    • NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2003/99771 A2, 2003 ; Location in patent: Page 112, 113 ; WO 03/099771 A2

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   3.4749
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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