Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N1-Methylbenzene-1,4-diamine

  • CAS No. 623-09-6

  • Cat. No. CS-0342994
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1-Methylbenzene-1,4-diamine|CS-0342994

Structure of 623-09-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 623-09-6
  • Cat. No. CS-0342994
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) 4-Amino-N-methylaniline
  • SMILES NC1=CC=C(NC)C=C1

Description

N1-Methylbenzene-1,4-diamine features a methylated primary amine and an unmodified secondary amine on a para-disubstituted benzene ring, delivering enhanced solubility and reactivity in nucleophilic substitution reactions. This dual functionality enables efficient coupling in polymer synthesis and pharmaceutical intermediates.

Application

N1-Methylbenzene-1,4-diamine serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds and functionalized aromatic systems. Its dual amine functionality, with one methylated nitrogen, provides enhanced solubility and controlled reactivity, facilitating selective transformations. The compound exhibits bench stability and compatibility with common coupling reactions, making it valuable for medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1
    • null|null
      100-15-2
    • ~99%
    • In-stock
      N1-Methylbenzene-1,4-diamine|CS-0342994
      623-09-6

    References

    • Hwang, Dong Jin; Yang, Jun; Xu, Huiping; Rakov, Igor M.; Mohler, Michael L.; Dalton, James T.; Miller, Duane D. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 19 p. 6525 - 6538
  • Route2
    • tert-butyl (4-(methylamino)phenyl)carbamate|CS-0215522
      113283-94-6
    • ~%
    • In-stock
      N1-Methylbenzene-1,4-diamine|CS-0342994
      623-09-6

    References

    • US2010/160332 A1, ; Page/Page column 7 ; US 20100160332 A1
  • Route3

    References

    • Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L. Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.3105
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N1-Methylbenzene-1,4-diamine sigmaN1-Methylbenzene-1,4-diamine manufacturerN1-Methylbenzene-1,4-diamine priceN1-Methylbenzene-1,4-diamine structureN1-Methylbenzene-1,4-diamine SDSbuy N1-Methylbenzene-1,4-diamineN1-Methylbenzene-1,4-diamine supplierN1-Methylbenzene-1,4-diamine usesN1-Methylbenzene-1,4-diamine molecular weightprice of N1-Methylbenzene-1,4-diamineN1-Methylbenzene-1,4-diamine chemical name formula of N1-Methylbenzene-1,4-diamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label