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CS-W001157 4
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tert-Butyl (4-aminophenyl)carbamate

  • CAS No. 71026-66-9

  • Cat. No. CS-W007514
  • Purity≥98%
  • MDL No.MFCD00043022

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (4-aminophenyl)carbamate|CS-W007514

Structure of 71026-66-9

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General Information

  • CAS No. 71026-66-9
  • Cat. No. CS-W007514
  • Purity ≥98%
  • MDL No. MFCD00043022
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆N₂O₂
  • Molecular Weight 208.26
  • Synonym(s) N-Boc-1,4-phenylenediamine
  • SMILES O=C(OC(C)(C)C)NC1=CC=C(N)C=C1

Description

tert-Butyl (4-aminophenyl)carbamate delivers a protected 4-aminophenyl moiety with enhanced stability and solubility in organic media. This bench-stable reagent integrates seamlessly into peptide and small-molecule synthesis, enabling efficient coupling and selective deprotection under mild conditions.

Synthesis

  • Route1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • null|null
      106-50-3
    • ~97%
    • In-stock
      tert-Butyl (4-aminophenyl)carbamate|CS-W007514
      71026-66-9

    References

    • Jung, Michael E.; Ouk, Samedy; Yoo, Dongwon; Sawyers, Charles L.; Chen, Charlie; Tran, Chris; Wongvipat, John Journal of Medicinal Chemistry, 2010 , vol. 53, # 7 p. 2779 - 2796
  • Route2

    References

    • LEGOCHEM BIOSCIENCE LTD. Patent: US2011/112083 A1, 2011 ; Location in patent: Page/Page column 15 ;
  • Route3
    • In-stock
      Di-tert-Butyl carbonate|CS-0146214
      34619-03-9
    • null|null
      106-50-3
    • ~96%
    • In-stock
      tert-Butyl (4-aminophenyl)carbamate|CS-W007514
      71026-66-9

    References

    • Takeda Pharmaceutical Company Limited Patent: EP1867331 A1, 2007 ; Location in patent: Page/Page column 52 ; EP 1867331 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.6158
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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