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CS-W001157 4
Total: USD 88.00

m-PEG2-acid

  • CAS No. 149577-05-9

  • Cat. No. CS-0105847
  • Purity≥96%
  • MDL No.MFCD09939037

*For research and further manufacturing use only, not for direct human use.

m-PEG2-acid|CS-0105847

Structure of 149577-05-9

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General Information

  • CAS No. 149577-05-9
  • Cat. No. CS-0105847
  • Purity ≥96%
  • MDL No. MFCD09939037
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₄
  • Molecular Weight 148.16
  • Synonym(s) None
  • SMILES OC(CCOCCOC)=O

Description

m-PEG2-acid features a short, hydrophilic polyethylene glycol spacer flanked by a reactive carboxylic acid group, enabling efficient conjugation in bioconjugation workflows. This bench-stable reagent facilitates site-specific attachment to amine-containing biomolecules while maintaining solubility in aqueous systems.

Application

m-PEG2-acid serves as a versatile, bench-stable linker for conjugation and macrocyclization workflows. Its terminal carboxylic acid enables efficient amide bond formation with amines under standard coupling conditions, while the short PEG2 spacer provides enhanced solubility and reduced aggregation. Ideal for peptide-drug conjugates and oligonucleotide modifications, it facilitates purification via ion-exchange chromatography and offers predictable behavior in aqueous environments.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.1241
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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