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CS-W001157 4
Total: USD 88.00

m-PEG2-CH2CH2COOH

  • CAS No. 209542-49-4

  • Cat. No. CS-0036728
  • Purity≥97%
  • MDL No.MFCD20646047

*For research and further manufacturing use only, not for direct human use.

m-PEG2-CH2CH2COOH|CS-0036728

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General Information

  • CAS No. 209542-49-4
  • Cat. No. CS-0036728
  • Purity ≥97%
  • MDL No. MFCD20646047
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O₅
  • Molecular Weight 192.21
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOC

Description

m-PEG2-CH2CH2COOH features a methoxy-terminated PEG2 chain linked to a reactive carboxylic acid group, enabling efficient conjugation in bioconjugation workflows. This bifunctional architecture combines hydrophilic stability with site-specific coupling potential, facilitating use in peptide modification, nanoparticle functionalization, and probe synthesis under mild aqueous conditions.

Application

m-PEG2-CH2CH2COOH serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the solubility and stability of a short PEG chain with a reactive carboxylic acid group. It enables efficient amide bond formation under standard coupling conditions, facilitating site-specific attachment to amines in peptides, proteins, or biomolecules. The molecule exhibits excellent bench stability and ease of purification, making it well-suited for use in diagnostic labeling, drug delivery systems, and solid-phase synthesis.

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   64.99
  • LogP   0.1407
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   9

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