Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(5-Methylpyrazin-2-yl)methanol

  • CAS No. 61892-95-3

  • Cat. No. CS-W006020
  • Purity≥98%
  • MDL No.MFCD11044903

*For research and further manufacturing use only, not for direct human use.

(5-Methylpyrazin-2-yl)methanol|CS-W006020

Structure of 61892-95-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 61892-95-3
  • Cat. No. CS-W006020
  • Purity ≥98%
  • MDL No. MFCD11044903
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 5-Methyl-2-pyrazinylmethanol
  • SMILES CC1=CN=C(C=N1)CO

Description

This bench-stable, moisture-tolerant (5-methylpyrazin-2-yl)methanol features a pyrazine core with a terminal hydroxymethyl group, enabling direct functionalization in synthetic routes. The methyl substituent enhances electron density at the ring, facilitating nucleophilic substitution and coupling reactions under mild conditions.

Application

(5-Methylpyrazin-2-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrazine-based scaffolds through functional group interconversions. Its primary alcohol functionality facilitates oxidation to the carboxylic acid or derivatization to esters and amides, while the electron-deficient pyrazine ring supports electrophilic substitution and transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.

Synthesis

  • Route1

    References

    • Dickschat, Jeroen S.; Wickel, Susanne; Bolten, Christoph J.; Nawrath, Thorben; Schulz, Stefan; Wittmann, Christoph European Journal of Organic Chemistry, 2010 , # 14 p. 2687 - 2695
  • Route2
    • 2-(Chloromethyl)-5-methylpyrazine hydrochloride|CS-0695928
      128229-06-1
    • ~76%
    • In-stock
      (5-Methylpyrazin-2-yl)methanol|CS-W006020
      61892-95-3

    References

    • Borsotti; Foa; Gatti Synthesis, 1990 , # 3 p. 207 - 208
  • Route3
    • 2,5-Dimethylpyrazine Glipizide  Impurity|CS-0229015
      123-32-0
    • ~%
    • In-stock
      (5-Methylpyrazin-2-yl)methanol|CS-W006020
      61892-95-3

    References

    • Organic Preparations and Procedures International, , vol. 23, # 2 p. 188 - 190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.01
  • LogP   0.27732
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • (5-Methylpyrazin-2-yl)methanol sigma(5-Methylpyrazin-2-yl)methanol manufacturer(5-Methylpyrazin-2-yl)methanol price(5-Methylpyrazin-2-yl)methanol structure(5-Methylpyrazin-2-yl)methanol SDSbuy (5-Methylpyrazin-2-yl)methanol(5-Methylpyrazin-2-yl)methanol supplier(5-Methylpyrazin-2-yl)methanol uses(5-Methylpyrazin-2-yl)methanol molecular weightprice of (5-Methylpyrazin-2-yl)methanol(5-Methylpyrazin-2-yl)methanol chemical name formula of (5-Methylpyrazin-2-yl)methanol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label