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CS-W001157 4
Total: USD 88.00

2-(2,4-Difluorophenyl)-5-methylpyridine

  • CAS No. 583052-21-5

  • Cat. No. CS-0062054
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2,4-Difluorophenyl)-5-methylpyridine|CS-0062054

Structure of 583052-21-5

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General Information

  • CAS No. 583052-21-5
  • Cat. No. CS-0062054
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉F₂N
  • Molecular Weight 205.20
  • Synonym(s) None
  • SMILES FC1=CC(F)=CC=C1C2=CC=C(C)C=N2

Description

This pyridine derivative features a 2,4-difluorophenyl group conjugated to a methyl-substituted pyridine core, delivering enhanced electron density and metabolic stability. It serves as a key scaffold in medicinal chemistry for kinase inhibitors and CNS-targeted therapeutics, offering favorable solubility and synthetic handle accessibility under standard conditions.

Application

2-(2,4-Difluorophenyl)-5-methylpyridine serves as a valuable building block in medicinal chemistry, enabling the construction of biologically active heterocyclic scaffolds. Its structural motif combines a fluorinated aromatic ring with a substituted pyridine core, offering enhanced metabolic stability and favorable pharmacokinetic properties. The compound exhibits good bench stability and facilitates diverse coupling reactions, making it well-suited for parallel synthesis campaigns targeting kinase inhibitors and CNS-active agents.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.33522
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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