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CS-W001157 4
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2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde

  • CAS No. 7310-95-4

  • Cat. No. CS-0130433
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde|CS-0130433

Structure of 7310-95-4

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General Information

  • CAS No. 7310-95-4
  • Cat. No. CS-0130433
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O₃
  • Molecular Weight 164.16
  • Synonym(s) 2-Hydroxy-5-methylisophthalaldehyde
  • SMILES O=CC1=CC(C)=CC(C=O)=C1O

Description

2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is a dialdehyde derivative. It has been synthesized by heating p-cresol with hexamethylenetetramine. The structure has been confirmed by 1H and 13C NMR. It is an important raw material for the synthesis of various binucleating schiff base ligand.2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde (2-hydroxy-5-methylisophthalaldehyde) is suitable reagent used in the synthesis of 2-(2-vinyloxyethoxy)-5-methylisophthaldehyde and chiral calixsalen macrocycles.2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde may be used in the synthesis of the following:3-[(2,4-Dichlorophenyl)iminomethyl]-2-hydroxy-5-methylbenzaldehyde, a Schiff base.2-Hydroxy-3-methoxymethyl-5-methylbenzaldehyde.Acyclic Schiff-base ligands.Macrobicyclic ligands (MSB).4-Methyl-2,6-divinylphenol.2-Hydroxy-3-dimethoxymethyl-5-methylbenzaldehyde.

Synthesis

  • Route1
    • null|null
      106-44-5
    • null|null
      100-97-0
    • ~69%
    • In-stock
      2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde|CS-0130433
      7310-95-4

    References

    • Hryniewicka, Agnieszka; Morzycki, Jacek W.; Witkowski, Stanislaw Journal of Organometallic Chemistry, 2010 , vol. 695, # 9 p. 1265 - 1270
  • Route2

    References

    • Syper; Mlochowski Synthesis, 1984 , vol. NO. 9, p. 747 - 752
  • Route3
    • null|null
      50-00-0
    • null|null
      106-44-5
    • ~35%
    • In-stock
      2-Hydroxy-5-methyl-1,3-benzenedicarboxaldehyde|CS-0130433
      7310-95-4

    References

    • Verani, Claudio Nazari; Rentschler, Eva; Weyhermueller, Thomas; Bill, Eckhard; Chaudhuri, Phalguni Journal of the Chemical Society, Dalton Transactions, 2000 , # 3 p. 251 - 258

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   54.37
  • LogP   1.32562
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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