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CS-W001157 4
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2-Methylmorpholine

  • CAS No. 27550-90-9

  • Cat. No. CS-D1584
  • Purity≥97%
  • MDL No.MFCD08444368

*For research and further manufacturing use only, not for direct human use.

2-Methylmorpholine|CS-D1584

Structure of 27550-90-9

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General Information

  • CAS No. 27550-90-9
  • Cat. No. CS-D1584
  • Purity ≥97%
  • MDL No. MFCD08444368
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) Morpholine, 2-methyl-
  • SMILES CC1CNCCO1

Description

2-Methylmorpholine is a bench-stable, moisture-tolerant heterocyclic amine featuring a tertiary nitrogen within a six-membered ring. This structure imparts enhanced nucleophilicity and solubility in polar organic solvents. It functions as a selective catalyst in C–N coupling reactions and serves as a key auxiliary in the synthesis of bioactive molecules.

Application

2-Methylmorpholine serves as a versatile nitrogen-containing heterocycle enabling efficient nucleophilic catalysis and phase-transfer applications. Its enhanced basicity and steric profile facilitate selective aminations and deprotonations in complex synthesis, while its bench stability and low volatility support reliable handling in industrial-scale processes. Functions as a key building block in API intermediates and catalyst design.

Synthesis

  • Route1
    • 1-(2-hydroxyethylamino)propan-2-ol|CS-M0804
      6579-55-1
    • ~%
    • In-stock
      2-Methylmorpholine|CS-D1584
      27550-90-9

    References

    • Sasanuma, Yuji; Kumagai, Ryota; Nakata, Kohji Macromolecules, 2006 , vol. 39, # 19 p. 6752 - 6764
  • Route2
    • null|null
      7664-93-9
    • 1-(2-hydroxyethylamino)propan-2-ol|CS-M0804
      6579-55-1
    • ~%
    • In-stock
      2-Methylmorpholine|CS-D1584
      27550-90-9

    References

    • Cottle et al. Journal of Organic Chemistry, 1946 , vol. 11, p. 289

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2920
Class : 8 (3)
Packing Group : Ⅱ
Hazard Statements : H226-H314-H318
Precautionary Statements : P210-P240-P241-P280-P370+P378

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   -0.0053
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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