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CS-W001157 4
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(S)-2-Methylmorpholine hydrochloride

  • CAS No. 1147108-99-3

  • Cat. No. CS-W006079
  • Molecule weight137.61
  • Purity≥98%
  • MDL No.MFCD11506701

*For research and further manufacturing use only, not for direct human use.

(S)-2-Methylmorpholine hydrochloride|CS-W006079

Structure of 1147108-99-3

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General Information

  • CAS No. 1147108-99-3
  • Cat. No. CS-W006079
  • Purity ≥98%
  • MDL No. MFCD11506701
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO
  • Molecular Weight 137.61
  • Synonym(s) (S)-2-METHYLMORPHOLINE HYDROCHLORIDE(WS200397)
  • SMILES C[C@H]1CNCCO1.[H]Cl

Description

(S)-2-Methylmorpholine hydrochloride is a chiral amine salt featuring a stereodefined morpholine ring with a methyl group at the 2-position. This bench-stable, moisture-tolerant compound serves as a selective ligand in asymmetric synthesis and catalysis. The protonated nitrogen enhances solubility in polar solvents while maintaining reactivity in transition-metal-catalyzed transformations.

Application

(S)-2-Methylmorpholine hydrochloride serves as a chiral auxiliary and versatile building block in asymmetric synthesis, enabling stereoselective transformations through its well-defined tertiary amine functionality. The hydrochloride salt enhances bench stability and solubility in polar solvents, facilitating efficient handling and purification. It functions effectively in nucleophilic substitution, metal-catalyzed coupling reactions, and as a scaffold for heterocyclic compound construction, particularly in medicinal chemistry applications requiring controlled stereochemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.4165
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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