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Structure of 25055-95-2
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This bench-stable diazirine derivative features a reactive methyl-substituted diazirinyl group tethered to an ethylamine chain, enabling efficient photoaffinity labeling under UV irradiation. The hydrochloride salt enhances solubility and handling in aqueous biological systems, facilitating site-specific protein crosslinking and target identification in live-cell environments.
2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine (hydrochloride) serves as a versatile photoaffinity labeling reagent, enabling site-specific covalent crosslinking upon UV irradiation. The diazirine moiety exhibits high stability under ambient conditions and reacts selectively with adjacent C–H and N–H bonds, facilitating the identification of protein-ligand interactions. Its amine functionality supports facile conjugation to biomolecules via standard coupling chemistries, while the hydrochloride salt enhances solubility and handling for aqueous-based applications.
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228-H315-H319
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Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378
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Lot numbers can be found on the outside label of a product: