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CS-W001157 4
Total: USD 88.00

2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine

  • CAS No. 36902-22-4

  • Cat. No. CS-0101343
  • Purity≥97%
  • MDL No.MFCD19204990

*For research and further manufacturing use only, not for direct human use.

2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine|CS-0101343

Structure of 36902-22-4

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General Information

  • CAS No. 36902-22-4
  • Cat. No. CS-0101343
  • Purity ≥97%
  • MDL No. MFCD19204990
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉N₃
  • Molecular Weight 99.13
  • Synonym(s) 3-Methyl-3H-diazirine-3-ethanamine
  • SMILES NCCC1(C)N=N1

Description

This diazirine-functional amine integrates a reactive, photoactivatable group with a primary amine handle, enabling covalent crosslinking upon UV irradiation. The methyl-substituted diazirine ring enhances stability while maintaining efficient singlet nitrogen extrusion. Ideal for labeling biomolecules and probing protein interactions in live systems.

Application

2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine serves as a stable, bench-ready photoreactive probe for site-specific protein crosslinking. Its methyl-substituted diazirine ring enables efficient UV-induced formation of reactive carbene intermediates, facilitating covalent attachment to proximal biomolecules. The primary amine functionality supports conjugation via standard coupling chemistries, enhancing versatility in chemical proteomics and target identification workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H226-H302-H314-H335
Precautionary Statements : P210-P260-P264-P270-P271-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   50.74
  • LogP   0.5172
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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