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CS-W001157 4
Total: USD 88.00

1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid

  • CAS No. 24334-20-1

  • Cat. No. CS-W021336
  • Purity≥90%
  • MDL No.MFCD11506121

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid|CS-W021336

Structure of 24334-20-1

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General Information

  • CAS No. 24334-20-1
  • Cat. No. CS-W021336
  • Purity ≥90%
  • MDL No. MFCD11506121
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight None
  • Synonym(s) 6-Azaindole-2-carboxylic acid
  • SMILES O=C(C(N1)=CC2=C1C=NC=C2)O

Description

1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid features a fused heterocyclic core combining pyrrole and pyridine moieties, delivering enhanced electron delocalization and rigidity. The carboxylic acid group enables direct functionalization or salt formation, supporting integration into pharmaceutical scaffolds and bioactive molecule synthesis under standard conditions.

Application

1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its rigid, planar scaffold enables efficient integration into bioactive molecules, while the carboxylic acid group facilitates direct derivatization or conjugation in standard coupling reactions. The compound exhibits good bench stability and compatibility with common functional groups, supporting its use in multi-step syntheses of pharmaceutical candidates and functional dyes.

Synthesis

  • Route1

    References

    • WO2004/104001 A2, ; Page 34 ; WO 2004/104001 A2
  • Route2

    References

    • European Journal of Medicinal Chemistry, , vol. 54, p. 660 - 668

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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