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1H-Pyrrolo[2,3-c]pyridine-2-carbaldehyde

  • CAS No. 867034-96-6

  • Cat. No. CS-0157274
  • Purity≥95%
  • MDL No.MFCD06738309

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[2,3-c]pyridine-2-carbaldehyde|CS-0157274

Structure of 867034-96-6

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General Information

  • CAS No. 867034-96-6
  • Cat. No. CS-0157274
  • Purity ≥95%
  • MDL No. MFCD06738309
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O
  • Molecular Weight 146.15
  • Synonym(s) 6-Azazindole-2-carboxyaldehyde
  • SMILES C1=C2C=C(C=O)NC2=CN=C1

Description

1H-Pyrrolo[2,3-c]pyridine-2-carbaldehyde features a fused heterocyclic core with a reactive aldehyde handle at the 2-position. This electron-deficient scaffold integrates readily into conjugated systems, enabling efficient coupling in synthetic transformations. The aldehyde group facilitates direct functionalization or incorporation into molecular architectures requiring site-specific derivatization.

Application

1H-Pyrrolo[2,3-c]pyridine-2-carbaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its aldehyde functionality enables direct incorporation into imine-based transformations, Ugi-type multicomponent reactions, and reductive amination protocols. The fused pyrrolopyridine core provides structural rigidity and enhanced metabolic stability, making it valuable in scaffold diversification for bioactive molecule development. Bench-stable and amenable to standard purification methods, it facilitates efficient access to complex nitrogen-containing architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.3754
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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