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CS-W001157 4
Total: USD 88.00

1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid

  • CAS No. 130473-27-7

  • Cat. No. CS-W021338
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid|CS-W021338

Structure of 130473-27-7

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General Information

  • CAS No. 130473-27-7
  • Cat. No. CS-W021338
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) 6-Azaindole-5-carboxylic acid
  • SMILES OC(=O)C1=CC2=C(NC=C2)C=N1

Description

1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry applications. This compound integrates seamlessly into bioactive molecules, leveraging its planar structure and carboxylic acid functionality for targeted conjugation and hydrogen bonding in drug discovery campaigns.

Application

1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its carboxylic acid functionality enables direct amidation, esterification, or coupling reactions under standard conditions. The fused pyrrolopyridine core exhibits good bench stability and functional group tolerance, facilitating incorporation into diverse scaffolds including bioactive molecules and conjugated polymers.

Synthesis

  • Route1

    References

    • Tetrahedron, , vol. 46, # 9 p. 3245 - 3266
  • Route2
    • 2-(1,3-Dioxolan-2-yl)-4-methyl-5-nitropyridine|CS-0689342
      119694-70-1
    • ~%
    • In-stock
      1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid|CS-W021338
      130473-27-7

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4425 - 4436
  • Route3
    • null|null
      130473-24-4
    • ~%
    • In-stock
      1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid|CS-W021338
      130473-27-7

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 14 p. 4425 - 4436

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.98
  • LogP   1.2611
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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