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CS-W001157 4
Total: USD 88.00

1-Methyl-1,7-diazaspiro[3.5]nonane dihydrochloride

  • CAS No. 2253108-14-2

  • Cat. No. CS-0167081
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1,7-diazaspiro[3.5]nonane dihydrochloride|CS-0167081

Structure of 2253108-14-2

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General Information

  • CAS No. 2253108-14-2
  • Cat. No. CS-0167081
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈Cl₂N₂
  • Molecular Weight 213.15
  • Synonym(s) None
  • SMILES CN1CCC12CCNCC2.[H]Cl.[H]Cl

Description

1-Methyl-1,7-diazaspiro[3.5]nonane dihydrochloride is a rigid, bicyclic amine salt featuring a spirocyclic framework that enhances conformational stability. The protonated nitrogen atoms deliver strong basicity and improved solubility in aqueous media, enabling efficient incorporation into synthetic intermediates and medicinal chemistry applications.

Application

1-Methyl-1,7-diazaspiro[3.5]nonane dihydrochloride serves as a conformationally constrained diamine building block, enabling efficient access to spirocyclic scaffolds in medicinal chemistry. Its protonated form enhances solubility and facilitates salt formation, while the rigid spiro structure provides defined stereochemistry for targeted ligand design. The compound exhibits robust bench stability and compatibility with standard coupling reactions, making it a practical choice for synthesizing complex heterocycles and bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   1.2877
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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