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CS-W001157 4
Total: USD 88.00

2-Methacrylamidoacetic acid

  • CAS No. 23578-45-2

  • Cat. No. CS-0158074
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methacrylamidoacetic acid|CS-0158074

Structure of 23578-45-2

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General Information

  • CAS No. 23578-45-2
  • Cat. No. CS-0158074
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NO₃
  • Molecular Weight 143.14
  • Synonym(s) N-Methacryloylglycine
  • SMILES C=C(C(NCC(O)=O)=O)C

Description

2-Methacrylamidoacetic acid features a methacrylamide group conjugated to a carboxylic acid, enabling efficient copolymerization and functionalization in aqueous environments. This bifunctional scaffold integrates seamlessly into polymer backbones for biomaterials and surface modification applications.

Application

2-Methacrylamidoacetic acid serves as a versatile building block in peptide and polymer synthesis, enabling efficient incorporation of acrylamide functionality via its pendant methacrylate group. Its amide-linked carboxylic acid moiety offers enhanced stability and solubility, facilitating straightforward conjugation and purification. Functions as a key monomer for hydrogel formation and bioconjugation applications.

Synthesis

  • Route1
    • Glycine, 99%|CS-1269057
      56-40-6
    • null|null
      920-46-7
    • ~63%
    • In-stock
      2-Methacrylamidoacetic acid|CS-0158074
      23578-45-2

    References

    • Ishikawa, Tomomichi; Tanaka, Youji Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 4 p. 1182 - 1185
  • Route2

    References

    • Brown, Eric; Loriot, Michel Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 9-10 p. 481 - 489
  • Route3
    • null|null
      79-41-4
    • Glycine, 99%|CS-1269057
      56-40-6
    • ~%
    • In-stock
      2-Methacrylamidoacetic acid|CS-0158074
      23578-45-2

    References

    • Biomedical Mass Spectrometry, , vol. 6, # 10 p. 439 - 443

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.4
  • LogP   -0.2367
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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