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CS-W001157 4
Total: USD 88.00

N-(2-Hydroxypropyl)methacrylamide

  • CAS No. 21442-01-3

  • Cat. No. CS-0115777
  • Purity≥98%
  • MDL No.MFCD00080531

*For research and further manufacturing use only, not for direct human use.

N-(2-Hydroxypropyl)methacrylamide|CS-0115777

Structure of 21442-01-3

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General Information

  • CAS No. 21442-01-3
  • Cat. No. CS-0115777
  • Purity ≥98%
  • MDL No. MFCD00080531
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.19
  • Synonym(s) None
  • SMILES C=C(C)C(NCC(O)C)=O

Application

N-(2-Hydroxypropyl)methacrylamide serves as a versatile hydrophilic monomer enabling the synthesis of functional polymers with tunable solubility and biocompatibility. Its pendant hydroxyl group facilitates conjugation, while the acrylamide functionality supports efficient free-radical polymerization. The molecule exhibits excellent bench stability, ease of purification, and compatibility with aqueous reaction conditions, making it well-suited for applications in responsive hydrogels, drug delivery systems, and surface modification.

Synthesis

  • Route1
    • In-stock
      1-Aminopropan-2-ol|CS-W016685
      78-96-6
    • null|null
      920-46-7
    • ~70%
    • In-stock
      N-(2-Hydroxypropyl)methacrylamide|CS-0115777
      21442-01-3

    References

    • Ebbesen, Morten F.; Schaffert, David H.; Crowley, Michael L.; Oupicky, David; Howard, Kenneth A. Journal of Polymer Science, Part A: Polymer Chemistry, 2013 , vol. 51, # 23 p. 5091 - 5099
  • Route2
    • null|null
      897017-30-0
    • ~%
    • In-stock
      N-(2-Hydroxypropyl)methacrylamide|CS-0115777
      21442-01-3

    References

    • Macromolecules, , vol. 36, # 20 p. 7491 - 7498
  • Route3
    • null|null
      675589-71-6
    • ~%
    • In-stock
      N-(2-Hydroxypropyl)methacrylamide|CS-0115777
      21442-01-3

    References

    • Macromolecules, , vol. 36, # 20 p. 7491 - 7498

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.0595
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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