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CS-W001157 4
Total: USD 88.00

1-Ethynyl-4-fluorobenzene

  • CAS No. 766-98-3

  • Cat. No. CS-W016580
  • Purity≥98%
  • MDL No.MFCD00168823

*For research and further manufacturing use only, not for direct human use.

1-Ethynyl-4-fluorobenzene|CS-W016580

Structure of 766-98-3

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General Information

  • CAS No. 766-98-3
  • Cat. No. CS-W016580
  • Purity ≥98%
  • MDL No. MFCD00168823
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅F
  • Molecular Weight 120.12
  • Synonym(s) 4-Fluorophenylacetylene
  • SMILES FC1=CC=C(C#C)C=C1

Description

1-Ethynyl-4-fluorobenzene (pFAB) is a fluorobenzene derivative. Trianionic pincer alkylidyne complex catalyzed polymerization of 1-ethynyl-4-fluorobenzene has been reported. The surface of the iodophenyl-terminated organic monolayers has been modified by Sonogashira coupling of the iodophenyl groups found on the surface with pFAB. Dimerization catalyzed by Y[N(TMS)2]3 and 4-chloroaniline gave exclusive formation of one of three possible enediynes in excellent yield.1-Ethynyl-4-fluorobenzene may be used in the synthesis of the following: 3-(4-Fluorophenyl)-1H-isochromen-1-one by reacting with 2-iodobenzoic acid in the presence of copper catalyst.4-Bromo-3,5-difluoro-2,6-bis-(4-fluoro-phenylethynyl)-pyridine by reacting with 2,4,6-tribromo-3,5-difluoropyridine by palladium catalyzed Sonogashira reaction. 1-(4-Fluorophenyl)-3-methoxy-3-(4-methoxyphenyl)propan-1-one by reacting with p-anisaldehyde.5-(4-Fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole by reacting with 1-(bromomethyl)-2-nitrobenzene in the presence of sodium azide.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H228-H315-H319-H335
Precautionary Statements : P210-P240-P241-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   1.807
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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