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CS-W001157 4
Total: USD 88.00

(E)-3-(2-Hydroxyphenyl)acrylic acid

  • CAS No. 614-60-8

  • Cat. No. CS-W013247
  • Purity≥98%
  • MDL No.MFCD00004379

*For research and further manufacturing use only, not for direct human use.

(E)-3-(2-Hydroxyphenyl)acrylic acid|CS-W013247

Structure of 614-60-8

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General Information

  • CAS No. 614-60-8
  • Cat. No. CS-W013247
  • Purity ≥98%
  • MDL No. MFCD00004379
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O₃
  • Molecular Weight 164.16
  • Synonym(s) None
  • SMILES O=C(O)/C=C/C1=CC=CC=C1O

Description

2-Hydroxycinnamic acid features a conjugated cinnamate backbone with an ortho-hydroxyl group, enabling intramolecular hydrogen bonding that enhances stability and influences reactivity. This structural motif supports efficient participation in coupling reactions and serves as a key scaffold in natural product synthesis and bioactive compound development.

Synthesis

  • Route1
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      3943-94-0
    • ~%
    • In-stock
      (E)-3-(2-Hydroxyphenyl)acrylic acid|CS-W013247
      614-60-8

    References

    • US6096918 A1, ;
  • Route2

    References

    • Justus Liebigs Annalen der Chemie, , vol. Suppl.8, p. 31 Justus Liebigs Annalen der Chemie, , vol. 59, p. 189 Annales de Chimie (Cachan, France), , vol. <3> 6, p. 345 Justus Liebigs Annalen der Chemie, , vol. 45, p. 334
  • Route3
    • null|null
      141-82-2
    • In-stock
      2-Methylbenzyl alcohol|CS-0152955
      89-95-2
    • ~47%
    • In-stock
      (E)-3-(2-Hydroxyphenyl)acrylic acid|CS-W013247
      614-60-8

    References

    • Simpson, Carol J.; Fitzhenry, Matthew J.; Stamford, N. Patrick J. Tetrahedron Letters, 2005 , vol. 46, # 40 p. 6893 - 6896

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.49
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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