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CS-W001157 4
Total: USD 88.00

2,5-Dimethyloxazole-4-carboxylic acid

  • CAS No. 23000-14-8

  • Cat. No. CS-0082121
  • Purity≥97%
  • MDL No.MFCD03011595

*For research and further manufacturing use only, not for direct human use.

2,5-Dimethyloxazole-4-carboxylic acid|CS-0082121

Structure of 23000-14-8

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General Information

  • CAS No. 23000-14-8
  • Cat. No. CS-0082121
  • Purity ≥97%
  • MDL No. MFCD03011595
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO₃
  • Molecular Weight None
  • Synonym(s) 2,5-Dimethyl-1,3-oxazole-4-carboxylic acid
  • SMILES O=C(C1=C(C)OC(C)=N1)O

Description

2,5-Dimethyloxazole-4-carboxylic acid features a rigid oxazole core with strategically positioned methyl and carboxylic acid groups, enabling direct incorporation into bioactive heterocycles. The electron-rich ring system enhances reactivity in coupling processes, while the carboxylic acid moiety facilitates derivatization under standard conditions. This bench-stable scaffold supports efficient synthesis of functionalized pharmaceutical intermediates.

Application

2,5-Dimethyloxazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to oxazole-containing scaffolds via standard coupling and cyclization protocols. Its stability under ambient conditions and compatibility with common functional groups facilitate straightforward purification and integration into diverse synthetic workflows. The carboxylic acid moiety provides a direct handle for amide formation, esterification, or activation in peptide-like conjugations, while the methyl-substituted oxazole core offers enhanced metabolic stability and favorable physicochemical properties in bioactive molecule design.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   0.98964
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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