(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid

Name: (R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid
Brand: ChemScene
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CAS No. 193693-63-9
Cat. No. CS-0155938
Purity≥98%
MDL No.MFCD06656475

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid|CS-0155938

Structure of 193693-63-9

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General Information

CAS No. 193693-63-9
Cat. No. CS-0155938
Purity ≥98%
MDL No. MFCD06656475
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₃NO₄
Molecular Weight 365.42
Synonym(s) (R)-(1-Fmoc-piperidin-2-YL)-acetic acid
SMILES C1=CC=C2C(=C1)C3=CC=CC=C3C2COC(=O)N4CCCC[C@@H]4CC(=O)O

Description

(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid is a chiral building block featuring a fluorenylmethyl carbamate-protected piperidine moiety and a pendant acetic acid group. This configuration enables direct incorporation into peptide synthesis workflows, where the fluorenylmethyl (Fmoc) group facilitates selective N-terminal protection. The molecule exhibits excellent stability under standard bench conditions and integrates seamlessly into solid-phase peptide synthesis protocols.

Application

(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid serves as a key chiral building block for the synthesis of peptidomimetics and bioactive molecules. The Fmoc-protected piperidine moiety enables efficient solid-phase peptide synthesis, while the (R)-configured acetic acid side chain provides stereochemical control in targeted conjugations. Its bench-stable nature and compatibility with standard coupling conditions facilitate reliable purification and scalability in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 66.84
LogP 4.2647
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-2-yl)acetic acid

CAS No. 193693-63-9

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