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CS-W001157 4
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Acid-PEG4-C2-Boc

  • CAS No. 1835759-85-7

  • Cat. No. CS-0046428
  • Purity≥98%
  • MDL No.MFCD29042335

*For research and further manufacturing use only, not for direct human use.

Acid-PEG4-C2-Boc|CS-0046428

Structure of 1835759-85-7

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General Information

  • CAS No. 1835759-85-7
  • Cat. No. CS-0046428
  • Purity ≥98%
  • MDL No. MFCD29042335
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₀O₈
  • Molecular Weight 350.40
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCC(O)=O

Description

Acid-PEG4-C2-Boc features a C2 spacer flanked by a Boc-protected amine and a carboxylic acid group, enabling selective conjugation in aqueous environments. The PEG4 linker provides enhanced solubility and reduced aggregation, while the Boc moiety offers stable protection under basic conditions. This derivative facilitates efficient bioconjugation workflows with minimal side reactions.

Application

Acid-PEG4-C2-Boc serves as a versatile, bench-stable linker for the synthesis of peptide- and oligonucleotide-based conjugates. The PEG4 spacer provides enhanced solubility and reduced aggregation, while the C2 linker enables efficient coupling to amine-functionalized substrates. The Boc group offers reliable protection of primary amines under mild acidic conditions, enabling orthogonal deprotection in multi-step syntheses. This reagent facilitates straightforward purification and is compatible with standard solid-phase and solution-phase workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   100.52
  • LogP   1.2593
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   15

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