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CS-W001157 4
Total: USD 88.00

Acid-PEG5-C2-Boc

  • CAS No. 1309460-29-4

  • Cat. No. CS-0114562
  • Purity≥98%
  • MDL No.MFCD18916989

*For research and further manufacturing use only, not for direct human use.

Acid-PEG5-C2-Boc|CS-0114562

Structure of 1309460-29-4

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General Information

  • CAS No. 1309460-29-4
  • Cat. No. CS-0114562
  • Purity ≥98%
  • MDL No. MFCD18916989
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₄O₉
  • Molecular Weight 394.46
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCC(O)=O

Description

Acid-PEG5-C2-Boc features a C2 spacer linking a terminal carboxylic acid to a PEG5 chain, terminated with a Boc group. This design enables site-specific conjugation in aqueous media while maintaining stability under standard conditions. The Boc moiety provides protection for amine functionalities during synthesis and purification workflows.

Application

Acid-PEG5-C2-Boc serves as a versatile, bench-stable linker for peptide and oligonucleotide conjugation, enabling efficient attachment of carboxylic acid-containing molecules via amide bond formation. The PEG5 spacer provides enhanced solubility and reduced aggregation, while the Boc group offers reliable protection of primary amines during synthesis. This reagent facilitates orthogonal functionalization in multi-step synthetic sequences and is compatible with standard coupling protocols used in medicinal chemistry and bioconjugation workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   109.75
  • LogP   1.2759
  • H_Acceptors   8
  • H_Donors   1
  • Rotatable_Bonds   18

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