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CS-W001157 4
Total: USD 88.00

Potassium (tert-butoxymethyl)trifluoroborate

  • CAS No. 910251-10-4

  • Cat. No. CS-0154664
  • Purity≥97%
  • MDL No.MFCD11505924

*For research and further manufacturing use only, not for direct human use.

Potassium (tert-butoxymethyl)trifluoroborate|CS-0154664

Structure of 910251-10-4

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General Information

  • CAS No. 910251-10-4
  • Cat. No. CS-0154664
  • Purity ≥97%
  • MDL No. MFCD11505924
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁BF₃KO
  • Molecular Weight 194.04
  • Synonym(s) Potassium tert-butoxymethyltrifluoroborate
  • SMILES CC(C)(C)OC[B-](F)(F)F.[K+]

Description

Potassium (tert-butoxymethyl)trifluoroborate serves as a stable, bench-friendly boronate source for Suzuki-Miyaura cross-coupling reactions. The tert-butoxymethyl group enhances solubility and minimizes protodeboronation, enabling efficient coupling under mild conditions. This reagent integrates seamlessly into synthetic workflows requiring selective C–C bond formation.

Application

Potassium (tert-butoxymethyl)trifluoroborate serves as a stable, bench-friendly boron building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoroborate group enables efficient C–C bond formation under mild conditions, with excellent functional group tolerance and compatibility with diverse substrates. The tert-butoxymethyl protecting group enhances stability and simplifies purification, making it a practical choice for the synthesis of complex molecular architectures in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   -0.8079
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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