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CS-W001157 4
Total: USD 88.00

TBS-PEG2-OH

  • CAS No. 131326-39-1

  • Cat. No. CS-0037215
  • Purity≥96%
  • MDL No.MFCD27943432

*For research and further manufacturing use only, not for direct human use.

TBS-PEG2-OH|CS-0037215

Structure of 131326-39-1

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General Information

  • CAS No. 131326-39-1
  • Cat. No. CS-0037215
  • Purity ≥96%
  • MDL No. MFCD27943432
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₄O₃Si
  • Molecular Weight 220.38
  • Synonym(s) None
  • SMILES OCCOCCO[Si](C)(C)C(C)(C)C

Description

This silyl-protected diol delivers orthogonal functional group compatibility in complex synthesis. The tert-butyldimethylsilyl ether stabilizes the primary alcohol, enabling selective transformations under standard conditions. Its hydrophilic ethylene glycol backbone enhances solubility in polar media while maintaining robust protection against nucleophiles and acids.

Application

2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-ol serves as a robust protecting group for primary alcohols, enabling orthogonal protection in complex molecule synthesis. Its silyl ether functionality offers excellent stability under a range of reaction conditions while permitting selective deprotection with fluoride sources. The compound facilitates efficient glycosylation and oligosaccharide assembly, and its ease of purification and bench stability enhance utility in multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.69
  • LogP   2.0171
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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