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Structure of 1807518-72-4
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Mal-PEG1-NHS ester is a bifunctional crosslinker featuring a maleimide group for selective thiol conjugation and a reactive NHS ester for amine coupling. This dual functionality enables efficient site-specific bioconjugation in aqueous environments, facilitating the synthesis of antibody-drug conjugates and peptide-protein hybrids under mild conditions.
Mal-PEG1-NHS ester serves as a versatile bifunctional linker for site-specific conjugation, combining the reactive NHS ester with a maleimide group. It enables efficient coupling to primary amines under physiological conditions, followed by rapid, selective Michael addition with thiols. Ideal for antibody-drug conjugates and bioconjugation workflows, it offers excellent stability in aqueous media and simplifies purification due to minimal side reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: