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Structure of 148673-97-6
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This benzoic acid derivative features a fused tetrahydropyrimidinone ring, combining a reactive 2,4-dioxo moiety with an aromatic carboxylate. The electron-deficient heterocycle enables efficient coupling reactions, while the carboxylic acid group facilitates conjugation and solubility in polar media. This scaffold integrates readily into bioactive molecule design, particularly for kinase inhibitors and nucleoside analogs.
2-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)benzoic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyrimidine-fused scaffolds via standard condensation and cyclization protocols. Its ortho-carboxylic acid functionality facilitates direct derivatization and enhances solubility in polar reaction media, while the 2,4-dioxo-tetrahydropyrimidine core exhibits predictable reactivity in nucleophilic addition and ring-closure transformations. The compound demonstrates bench stability and compatibility with common protecting group strategies, supporting its use in iterative synthetic sequences and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: