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CS-W001157 4
Total: USD 88.00

2-Fluoropyridine-5-boronic acid

  • CAS No. 351019-18-6

  • Cat. No. CS-D1045
  • Purity≥97%
  • MDL No.MFCD03411559

*For research and further manufacturing use only, not for direct human use.

2-Fluoropyridine-5-boronic acid|CS-D1045

Structure of 351019-18-6

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General Information

  • CAS No. 351019-18-6
  • Cat. No. CS-D1045
  • Purity ≥97%
  • MDL No. MFCD03411559
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BFNO₂
  • Molecular Weight 140.91
  • Synonym(s) 6-Fluoropyridine-3-boronic acid
  • SMILES FC1=CC=C(B(O)O)C=N1

Synthesis

  • Route1

    References

    • KINEX PHARMACEUTICALS, LLC Patent: WO2009/51848 A1, 2009 ; Location in patent: Page/Page column 65 ; WO 2009/051848 A1
  • Route2
    • In-stock
      5-Bromo-2-fluoropyridine|CS-D0938
      766-11-0
    • null|null
      121-43-7
    • ~61%
    • In-stock
      2-Fluoropyridine-5-boronic acid|CS-D1045
      351019-18-6

    References

    • ABBOTT LABORATORIES Patent: WO2004/80973 A1, 2004 ; Location in patent: Page 116-117 ; WO 2004/080973 A1
  • Route3

    References

    • Carroll; Liang; Navarro; Brieaddy; Abraham; Damaj; Martin Journal of Medicinal Chemistry, 2001 , vol. 44, # 13 p. 2229 - 2237

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -1.0995
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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