tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate

Name: tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate
Brand: ChemScene
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CAS No. 145106-43-0
Cat. No. CS-0039168
Purity≥97%
MDL No.MFCD11656038

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate|CS-0039168

Structure of 145106-43-0

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Description

tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate features a chiral cyclopentane scaffold with a hydroxyl group in the cis configuration, enabling stereocontrolled synthesis. The tert-butyloxycarbonyl (Boc) group provides robust protection for amine functionalities under acidic conditions. This bifunctional reagent integrates seamlessly into complex molecule assembly workflows, offering high stability and predictable reactivity in peptide and natural product synthesis.

Application

tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate serves as a versatile chiral building block for asymmetric synthesis, enabling efficient construction of cyclopentane-based scaffolds. The protected amine and secondary alcohol functionalities exhibit excellent bench stability and compatibility with standard coupling and functionalization protocols. Its orthogonal reactivity facilitates sequential transformations in complex molecule assembly, particularly in medicinal chemistry and natural product synthesis.

General Information

CAS No. 145106-43-0
Cat. No. CS-0039168
Purity ≥97%
MDL No. MFCD11656038
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₃
Molecular Weight 201.26
Synonym(s) (1S,2S)-trans-N-Boc-2-aminocyclopentanol
SMILES O=C(OC(C)(C)C)N[C@@H]1[C@@H](O)CCC1

Computational Chemistry Data

TPSA 58.56
LogP 1.4245
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07,GHS08,GHS09
Signal Word : Danger	UN#: 3077
Class : 9	Packing Group : Ⅲ
Hazard Statements : H302-H372-H400
Precautionary Statements : P260-P264-P273-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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tert-Butyl N-[(1S,2S)-2-hydroxycyclopentyl]carbamate

CAS No. 145106-43-0

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