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CS-W001157 4
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tert-Butyl (2-hydroxycyclopentyl)carbamate

  • CAS No. 945652-35-7

  • Cat. No. CS-0102135
  • Purity≥95%
  • MDL No.MFCD09261198
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-hydroxycyclopentyl)carbamate|CS-0102135

Structure of 945652-35-7

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Description

tert-Butyl (2-hydroxycyclopentyl)carbamate features a hydroxyl-functionalized cyclopentyl scaffold protected as a carbamate, enabling stable incorporation into complex molecular architectures. This bench-stable reagent facilitates selective derivatization under mild conditions, offering reliable access to oxygenated cyclic intermediates in synthetic and medicinal chemistry workflows.

Application

tert-Butyl (2-hydroxycyclopentyl)carbamate serves as a versatile protected amine building block in synthetic organic chemistry, enabling controlled functionalization of cyclopentyl scaffolds. The carbamate group provides excellent bench stability and orthogonal deprotection compatibility, while the pendant hydroxyl group allows for selective derivatization via esterification or ether formation. It functions effectively in multistep synthesis workflows, particularly in medicinal chemistry campaigns requiring stereochemically defined cyclic amines.

General Information

  • CAS No. 945652-35-7
  • Cat. No. CS-0102135
  • Purity ≥95%
  • MDL No. MFCD09261198
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₃
  • Molecular Weight 201.26
  • Synonym(s) trans- N-(tert-butyloxycarbonyl)-2-hydroxycyclopentylamine
  • SMILES O=C(NC1C(CCC1)O)OC(C)(C)C

Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.4245
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group :
Hazard Statements : H302-H372-H400
Precautionary Statements : P260-P264-P270-P273-P330-P391-P501

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