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tert-Butyl (2-hydroxycyclopentyl)carbamate

  • CAS No. 945652-35-7

  • Cat. No. CS-0102135
  • Purity≥95%
  • MDL No.MFCD09261198

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-hydroxycyclopentyl)carbamate|CS-0102135

Structure of 945652-35-7

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General Information

  • CAS No. 945652-35-7
  • Cat. No. CS-0102135
  • Purity ≥95%
  • MDL No. MFCD09261198
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₃
  • Molecular Weight 201.26
  • Synonym(s) trans- N-(tert-butyloxycarbonyl)-2-hydroxycyclopentylamine
  • SMILES O=C(NC1C(CCC1)O)OC(C)(C)C

Description

tert-Butyl (2-hydroxycyclopentyl)carbamate features a hydroxyl-functionalized cyclopentyl scaffold protected as a carbamate, enabling stable incorporation into complex molecular architectures. This bench-stable reagent facilitates selective derivatization under mild conditions, offering reliable access to oxygenated cyclic intermediates in synthetic and medicinal chemistry workflows.

Application

tert-Butyl (2-hydroxycyclopentyl)carbamate serves as a versatile protected amine building block in synthetic organic chemistry, enabling controlled functionalization of cyclopentyl scaffolds. The carbamate group provides excellent bench stability and orthogonal deprotection compatibility, while the pendant hydroxyl group allows for selective derivatization via esterification or ether formation. It functions effectively in multistep synthesis workflows, particularly in medicinal chemistry campaigns requiring stereochemically defined cyclic amines.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H372-H400
Precautionary Statements : P260-P264-P270-P273-P330-P391-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.4245
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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