(1S,2R)-2-Aminocyclopentanol hydrochloride

Name: (1S,2R)-2-Aminocyclopentanol hydrochloride
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CAS No. 225791-13-9
Cat. No. CS-W003557
Purity≥97%
MDL No.MFCD08704797

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(1S,2R)-2-Aminocyclopentanol hydrochloride|CS-W003557

Structure of 225791-13-9

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General Information

CAS No. 225791-13-9
Cat. No. CS-W003557
Purity ≥97%
MDL No. MFCD08704797
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO
Molecular Weight 137.61
Synonym(s) Cis-(1S,2R)-2-Amino-Cyclopentanol Hydrochloride
SMILES O[C@H]1CCC[C@H]1N.Cl

Description

This chiral cyclopentanol derivative features a stereochemically defined amine and hydroxyl group, enabling precise integration into asymmetric synthesis. The hydrochloride salt enhances solubility and stability in aqueous media, facilitating use in catalytic systems and peptide backbone modifications under standard conditions.

Application

(1S,2R)-2-Aminocyclopentanol hydrochloride serves as a stereochemically defined chiral building block for the synthesis of bioactive heterocycles and medicinal intermediates. Its well-defined stereocenters enable predictable diastereoselective transformations, while the amine and hydroxyl functionalities offer orthogonal reactivity for coupling and protection strategies. The hydrochloride salt enhances bench stability and solubility, facilitating straightforward handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

TPSA 46.25
LogP 0.2803
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Key Words

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(1S,2R)-2-Aminocyclopentanol hydrochloride

CAS No. 225791-13-9

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