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CS-W001157 4
Total: USD 88.00

3-Methyl-4-morpholinophenylboronicacid

  • CAS No. 1426245-63-7

  • Cat. No. CS-0061269
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methyl-4-morpholinophenylboronicacid|CS-0061269

Structure of 1426245-63-7

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General Information

  • CAS No. 1426245-63-7
  • Cat. No. CS-0061269
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BNO₃
  • Molecular Weight 221.06
  • Synonym(s) 3-Methyl-4-morpholinophenylboronic acid
  • SMILES CC1=CC(=CC=C1N2CCOCC2)B(O)O

Description

3-Methyl-4-morpholinophenylboronic acid features a morpholine ring appended to a boronic acid-functionalized aromatic scaffold, delivering enhanced solubility and stability under standard conditions. The electron-rich aryl moiety facilitates efficient cross-coupling reactions, while the methyl group provides steric control. This compound integrates seamlessly into Suzuki-Miyaura coupling workflows for constructing complex biaryl architectures in medicinal chemistry and materials synthesis.

Application

3-Methyl-4-morpholinophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its morpholine moiety enhances solubility and stability, while the boronic acid group facilitates reliable coupling under mild conditions. The methyl substituent provides steric and electronic modulation, improving functional group tolerance and simplifying purification—making it well-suited for medicinal chemistry and process-scale synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.48858
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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