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CS-W001157 4
Total: USD 88.00

2-(Morpholino)phenylboronic acid

  • CAS No. 933052-52-9

  • Cat. No. CS-W020550
  • Purity≥98%
  • MDL No.MFCD03095109

*For research and further manufacturing use only, not for direct human use.

2-(Morpholino)phenylboronic acid|CS-W020550

Structure of 933052-52-9

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General Information

  • CAS No. 933052-52-9
  • Cat. No. CS-W020550
  • Purity ≥98%
  • MDL No. MFCD03095109
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BNO₃
  • Molecular Weight 207.03
  • Synonym(s) (2-Morpholinophenyl)boronic acid
  • SMILES OB(C1=CC=CC=C1N2CCOCC2)O

Description

2-(Morpholino)phenylboronic acid features a boronate moiety appended to a phenyl ring bearing a morpholino substituent, enabling efficient coupling in Suzuki-Miyaura reactions. The electron-rich morpholino group enhances solubility and stabilizes the boron center under physiological conditions. This bench-stable reagent integrates seamlessly into complex molecule synthesis workflows.

Application

2-(Morpholino)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The morpholino group enhances solubility and modulates electronic properties, while the boronic acid functionality offers excellent stability, ease of purification, and compatibility with diverse functional groups. This reagent functions reliably in late-stage diversification and heterocycle synthesis, supporting scalable, bench-friendly workflows for medicinal chemistry and materials applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.797
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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